Which of the following could be a contraindication to prescribing a thiazide diuretic? a. Ulcer disease. b. Pulmonary fibrosis. c. Mild renal disease. d. Sulfa allergy.

The correct answer is d. Sulfa allergy.<br /><br />Thiazide diuretics are a class of medications commonly used to treat conditions such as hypertension and edema. However, there are certain contraindications or conditions that may make the use of thiazide diuretics inappropriate or unsafe for some individuals.<br /><br />In this case, a sulfa allergy is a contraindication to prescribing a thiazide diuretic. Thiazide diuretics, such as hydrochlorothiazide, contain a sulfonamide group, which can trigger an allergic reaction in individuals with a sulfa allergy. This allergic reaction can manifest as skin rash, itching, or even more severe symptoms like anaphylaxis in some cases.<br /><br />The other options provided are not contraindications for thiazide diuretics:<br /><br />a. Ulcer disease: Thiazide diuretics do not have a direct impact on ulcer disease, and there is no known contraindication.<br /><br />b. Pulmonary fibrosis: Thiazide diuretics are not contraindicated in patients with pulmonary fibrosis. In fact, they can be beneficial in managing fluid retention associated with this condition.<br /><br />c. Mild renal disease: Thiazide diuretics can be used cautiously in patients with mild renal disease. They are often preferred over loop diuretics in such cases due to their lower risk of causing electrolyte imbalances.<br /><br />Therefore, the correct answer is d. Sulfa allergy, as it is a contraindication to prescribing a thiazide diuretic.