When the skin comes In contact with an Irritant, receptors in the skin send signals to the spinal cord. The signal is then sent to the brain for processing, and the Individual begins to scratch the affected area. Which two systems are most likely interacting when a person experiences itching caused by a skin Irritant? Circulatory and excretory Digestive and muscular Integumentary and nervous Respiratory and lymphatic

## Step 1<br />The problem describes a situation where the skin comes into contact with an irritant. This send signals to the spinal cord. The signal is then sent to the brain for processing, which leads to the individual scratching the affected area.<br /><br />## Step 2<br />The process described above involves two systems of the body. The first system is the integumentary system, which includes the skin and its associated structures. This system is responsible for protecting the body from external irritants and pathogens.<br /><br />## Step 3<br />The second system involved is the nervous system. This system is responsible for transmitting signals from the skin to the brain. The brain then processes this information and sends a response, which is the urge to scratch the affected area.