The energy required to run the Calvin cycle reactions of photosynthesis comes from which two substances produced during the light dependent reactio A O_(2) and CO_(2) B ADP and PO_(4) C ATP and NADPH D H^+ and PO_(2) E H_(2)O and CO_(2)

The Calvin cycle, also known as the light-independent reactions or the dark reactions of photosynthesis, requires energy to convert carbon dioxide into glucose. This energy comes from ATP and NADPH, which are produced during the light-dependent reactions of photosynthesis. Therefore, the correct answer is C: ATP and NADPH.